|
Dangerous
Cells!
Meet The
Chlamydiae! Top Nuts!
Buncefield Fire, Himalaya Quakes!
Mapping
Dark Matter! |
| Dangerous
Cells! |

On the surface, she said, it appears that drivers are
trying to accomplish just two tasks driving and
conversing. But each task is complicated and multi-
faceted, greatly increasing the "cost" of switching.
(US Census Bureau) |
Driving Cells
Oregon
State University News Release
December 9, 2005 - Most people can rather efficiently walk and chew gum at
the same time, but when it comes to more complicated
"multi-tasking" like driving and talking on a cell phone
there is a price to pay.
And no one, it seems, is immune.
"There is a cost for switching from one task to another and that cost
can be in response time or in accuracy," said
Mei-Ching Lien, an assistant professor of psychology at Oregon State
University. "Even with a seemingly simple task, structural cognitive
limitations can prevent you from efficiently switching to a new
task."
Psychologists who study multi-tasking have argued for years about whether
these "information bottlenecks" occur because people are
inherently lazy, or because they have a fundamental inability to switch
from one task to another. New studies by Lien and her colleagues at the
NASA Ames Research Center in California suggest it is the latter.
Results of their study have been published in the Journal of Experimental
Psychology.
In their study the researchers asked volunteers to respond to a variety of
auditory and visual cues then measured the responses. When the volunteers
prepared for one task, such as responding to the color red, their
responses were swift and accurate. When the researchers added a second
element the recognition of shapes as well as color the task switch
considerably delayed the responses, even when the volunteers were prepared
for it.
 |
"People are
surprised that there is such a delay," Lien said. "Practice can
help a person reduce the 'cost' of switching tasks, but it apparently
cannot eliminate that cost."
Lien said the study can be applied to the real world, especially to
drivers who talk on cell phones. On the surface, she said, it appears that
drivers are trying to accomplish just two tasks driving and
conversing. But each task is complicated and multi-faceted, greatly
increasing the "cost" of switching. The result: inattention and
slow reaction times.
"A lot of people think talking on the cell phone while driving is
natural, but each time someone asks a question or changes the subject,
it's like taking on a new task," Lien said. "It requires a
certain amount of thought and preparation. It's actually quite different
than listening to the radio, where you don't need to respond.
"And it's also different from talking to a passenger in the
vehicle," she added. "In most cases, a passenger can observe
when there is a dangerous traffic situation and keep quiet. But someone
calling you on a cell phone won't have a clue."
There are individual differences in the costs of multi-tasking, Lien said.
In her lab studies, a typical response to a single stimulus might take 300
milliseconds. Adding a second task increases the response to about 800
milliseconds. A millisecond is 1/1000th of a second, so the delay may not
seem like much until you extend the difference to a car driving 60
miles an hour and realize the response rate more than doubles, Lien said.
 |
In her lab studies,
she has yet to test any volunteers who are immune to delays in
multi-tasking, though she says some students do much better than others.
"I have to say that the best ones are those who play a lot of video
games," she pointed out. "Those are lab studies, however, and
not driving tests."
She became interested in multi-tasking while working at the NASA Ames
Research Center in Moffett, Calif., where she was part of a team analyzing
cockpit design and pilot function. One of the projects focused on how much
information can safely and efficiently be included on screens and monitors
so the pilots' delay and loss of accuracy are minimized.
"We learned to modify some of the screens to mitigate their
weaknesses," she said.
While Lien's studies suggest that simplifying tasks leads to greater
efficiency, technology is complicating everything we do including
driving. Drivers often use cell phones, CD players, global positioning
systems, radar detectors, complicated dashboards and other devices. At the
same time, they must navigate increasing traffic, read a plethora of
signs, and handle other distractions.
"We may be undermining our ability to drive safely," Lien said.
Oregon State University - http://www.orst.edu
Cell Phones
Increase Distress Level
Blackwell
Publishing Ltd. News Release

Andrew
Wielawski's sculpture
"Nude With Cell Phone" (1997) |
December 12, 2005 -
The ongoing use of this communications technology, as compared to
computer-based use such as email, is linked to increased psychological
distress and reduced family satisfaction.
For both men and
women, cell phones allow job worries to spill over into home life. But
only women also experience the opposite effect--the spillover of home
concerns into their work life. For
women, both work and family worries and responsibilities affected their
levels of distress and family satisfaction.
The findings suggest that, although technology may make everyone more
accessible, it does so with negative consequences.
The authors
interviewed working couples over two time periods, 1998-1999 and
2000-2001. Use of cell phones and pagers in that two-year time period
decreased family satisfaction and increased distress, and negative
work-to-family (for men and women) and family-to-work (for women)
spillover.
The author measured
the participants' psychological distress; she asked them to state how
often in the past month they felt feelings ranging from "in good
spirits" to "everything was an effort."
Participants were also asked questions such as whether they could turn to
their family for help and if they were satisfied with the support they
receive.
"The question of 'blurred boundaries' may become an irrelevant one
for the next generation of workers, spouses, and parents because they
cannot imagine life any other way," the author states.
"Even so,
worries about the implications for technology users are not likely to
disappear."
This study is published in the December issue of the Journal of Marriage
and Family.
Blackwell Publishing Ltd. - http://www.blackwellpublishing.com |
| Meet
The Chlamydiae! |

Chlamydiae are intracellular parasites that get vitamins,
amino acids, ATP, and other vital cellular molecules from
their host cell. Chlamydia trachomatis, a species within
this phylum, causes a venereal disease in humans that is
commonly referred to as "chlamydia" or
"trachoma," and
Chlamydophila pneumoniae causes a type of pneumonia
that that creates chest infections. (Sidwell Friends School) |
American Society
for Cell Biology News Release
December 11, 2005 - Invasive bacterial pathogens, the Chlamydiae know us
very, very well. The Chlamydiae learned to parasitize eukaryotic cells
half a billion years ago by reprogramming cellular functions from within.
In humans today, chlamydial infections are responsible for a range of
ailments from sexually transmitted infections to atypical pneumonias to
chronic severe disorders such as pelvic inflammatory disease and
atherosclerosis. The Centers for Disease Control says that Chlamydia
trachomatis is the most common sexually-transmitted infection in the US,
with three million new cases a year.
Chlamydia gets around because it knows its hosts so well. It's an
"obligate intracellular parasite" which means that it relies on
its eukaryotic host for everything from reproduction to synthesizing ATP,
all while living inside a membrane-bounded vacuole that provides a
protected, fertile environment for the bacteria to grow and multiply.
Because lipid
acquisition from the host is necessary for chlamydial replication, these
pathogens are essentially lipid parasites. So, to add insult to injury,
Chlamydia apparently lives on our fat.
Lipid droplets are fat-rich structures found in all eukaryotic cells. In
humans, lipid droplets are abundant in adipocytes, our professional fat
storage cells, where they have traditionally been regarded as passive
storage depots of excess fat. However, recent studies have reassessed
their role. Lipid droplets are now known to be motile, dynamic and
enriched for proteins known to regulate lipid synthesis, membrane traffic
and cell signaling.
Now in new research
presented Sunday at the 45th Annual Meeting of the American Society for
Cell Biology in San Francisco, Yadunanda Kumar and Raphael Valdivia of
Duke University Medical Center report that Chlamydia loves our lipid
droplets.

Scanning electron micrograph of a chlamydia
inclusion body leaving a host cell in a dramatic
fashion. The inset shows a closeup of the
elementary bodies breaking free of the inclusion
body. (UBC Centre for Disease Control) |
The discovery of an
interaction between lipid droplets and Chlamydia was made as Kumar and
Valdivia performed the genetic equivalent of an end-run. Chlamydia is not
amenable to direct genetic manipulation so the researchers moved the
pathogen's genes elsewhere, inserting them into the eukaryotic cells of
baker's yeast. The resulting chlamydial proteins were screened for those
that targeted to yeast intracellular organelles. They identified four
proteins that were specifically recruited to lipid droplets.
The researchers found that Chlamydia not only directs lipid droplets to
its protective vacuole but also causes the proliferation of new lipid
droplets on the host. The co-option of lipid droplets appears to be
essential for Chlamydia pathogenesis. When the researchers used drugs to
inhibit lipid droplet formation in the host, they sharply impaired
bacterial growth.
That finding immediately presents a new target for anti-Chlamydia drugs
but it also suggests an entirely novel pathogenic mechanism. "We
propose that Chlamydia use lipid droplets in a previously unknown pathway
for lipid acquisition," says Kumar. "Alternatively, it is
possible that the recruitment of lipid droplets constitutes an example of
'organelle mimicry' where Chlamydia escapes recognition by the host by
cloaking itself in these fat-rich structures."
Understanding host lipid transport by Chlamydiae may have further
implication for chronic infections, the researchers say. For example,
lipid-rich macrophages ("foam cells") are a symptom in
chlamydial pneumonia. Because foam cells are a key element in development
of atherosclerosis, lipid droplet co-option also suggests a possible
explanation for the association between chlamydial infections and heart
disease.
American Society for Cell Biology - http://www.ascb.org |
| Top
Nuts for Good Health |
 |
American Chemical
Society News Release
December 7, 2005 - Researchers have known for some time that nuts and
seeds are rich sources of phytosterols, a class of plant chemicals that
have been shown to reduce cholesterol levels and improve heart health.
In what is believed to be the most comprehensive analysis to date of the
phytosterol content of nuts and seeds, chemists at Virginia Polytechnic
Institute and State University in Blacksburg, Va., analyzed some 27 nut
and seed products and found that pistachios and sunflower kernels had the
highest levels of phytosterols among the nuts and seeds that are most
commonly consumed as snack foods in the United States.
Their study appears in the Nov. 30 issue of the American Chemical
Society's Journal of Agricultural and Food Chemistry.
Sesame seed and wheat germ actually ranked highest but are not consumed as
frequently as individual foods, the researchers say. Brazil nuts and
walnuts ranked the lowest in phytosterols, they say. The chemists caution
that phytosterols are not the only food component involved in lowering
cholesterol and that other compounds may also play a role. A well-balanced
diet and frequent exercise are important keys to good health, they stress.
The American Chemical Society is a nonprofit organization, chartered by
the U.S. Congress, with a multidisciplinary membership of more than
158,000 chemists and chemical engineers. It publishes numerous scientific
journals and databases, convenes major research conferences and provides
educational, science policy and career programs in chemistry. Its main
offices are in Washington, D.C., and Columbus, Ohio.
American Chemical Society - http://www.acs.org |
| Buncefield
Oil Depot Fire Blackens London |

London covered by oil fire (ESA) |
European Space
Agency News Release
December 12, 2005 - London is completely blanketed by the black plume of
smoke from Europe's worst peacetime fire in this Envisat image, taken
within five hours of the blaze beginning.
This image was acquired at 10:45 GMT on Sunday morning by the Medium
Resolution Imaging Spectrometer (MERIS), one of ten instruments aboard
Envisat, Europe's largest satellite for environmental monitoring. This
Reduced Resolution mode image has a spatial resolution of 1200 metres, and
shows the cloud spread across a span of around 140 km.
The pall of smoke comes from a fire at Buncefield oil depot on the
outskirts of Hemel Hempstead. Buncefield is the fifth largest fuel storage
depot in the UK, distributing millions of tonnes of petrol and other oil
products per year, including aviation fuel to nearby Luton and Heathrow
Airports.
Buncefield is located at the topmost part of the cloud, with light winds
blowing the smoke south-west and south-east to cover a large part of
Southern England. On Monday morning firefighters began laying down 250 000
litres of foam to control the blaze, which is reported to be the largest
industrial fire in Europe since 1945.
The fire began with a series of explosions taking place on Sunday morning
at around 06:00 GMT. Nobody was killed in the explosion but 43 people have
been injured, and more than 2000 people have been evacuated from the
vicinity of the depot.
All but seven out of 26 storage tanks at the depot are currently burning
each tank contains more than 13 million litres of fuel. Health experts
have warned susceptible people to avoid breathing in the acrid black
smoke. The heat of the fire has driven smoke particles high into the sky,
with aircraft reporting pollution reaching above 2750 metres, and the
cloud stretching from East Anglia to Salisbury Plain.
European Space Agency - http://www.esa.int |
| Himalaya
Quakes! |

Himalaya
Mountains from space (NASA) |
University of
Colorado at Boulder News Release
December 7, 2005 - While the rupture zones of recent major earthquakes are
immune to similar-sized earthquakes for hundreds of years, they could be
vulnerable to even bigger destructive temblors sooner than scientists
suspect, according to analysis by University of Colorado seismologist
Roger Bilham.
Bilham and his research colleagues explained that the magnitude 9.3 Indian
Ocean earthquake of December 2004 showed scientists that a giant
earthquake can rupture through a region with a recent history of quakes
with magnitudes as large as 7.9 on the Richter Scale.
"Following what we learned in 2004, we believe that regions of the
Himalaya that have recently experienced magnitude 7.8 earthquakes - like
the Kangra district, a hundred years ago - may not be immune to a future
larger earthquake," he said.
Bilham's research of Himalayan earthquakes in the last 1,000 years is part
of findings presented in an invited talk, "Unprecedented massive
earthquakes in the Himalaya driven by elastic strain stored within the
Tibetan Plateau?" Dec. 7 at the American Geophysical Union's fall
meeting in San Francisco.
Bilham recently returned from Kashmir, where he conducted a series of
measurements along with Pakistani scientists to assess subsurface fault
slip and damage in that region's October earthquake.
"The Kashmir event released almost 100 times less energy than the
Sumatra-Andaman quake in 2004," he said. "The Kashmir rupture
was about 16 times smaller in length and five times smaller in width, yet
it flattened whole cities in its path."
The Kashmir earthquake was the deadliest earthquake ever in the Indian
subcontinent, mostly because of the poor construction quality in the area,
Bilham said. "Most of the buildings that collapsed had been
constructed in the past two decades.
"It is distressing to see how little attention has been focused on
this earthquake by news media in the United States," he said.
Bilham believes medieval earthquakes beneath the Himalaya may have been
larger than any in the past 300 years. Bilham and his colleagues are
trying to determine what governs the recurrence interval and the size of
these historically much larger earthquakes.

Geographical
repartition of the last big Himalayan
earthquakes : Western and Center Nepal had been
spared since at least two centuries. (National
Seismological Centre, Nepal) |
"We postulate
that a giant reservoir of elastic energy exists not just in the Himalaya
but also beneath southern Tibet," he said. "This reservoir of
energy is tapped by Himalayan earthquakes more efficiently if ruptures are
geographically long."
Bilham and his colleagues developed a "theoretical law" linking
earthquakes of different size to their geographic length and repeat time.
They concluded that recent earthquakes require about 500 years to repeat,
but the medieval ones require almost 2,000 years.
"We suggest that these rare events must have exploited much longer
ruptures than any we have seen recently, like those that slipped in the
Kangra and Kashmir earthquakes," he said. "We find also that
these rare great events can re-rupture parts of the plate boundary that
slip in modest earthquakes up to magnitude 7.6. As a result, recent
rupture zones could be vulnerable to greater destruction sooner than one
might suspect from India's rate of approach toward Asia."
The tremendous Indian Ocean earthquake in 2004 gave seismologists an
unprecedented look at the mechanics of the world's largest earthquakes.
Using data recorded by digital seismometers all over the world, scientists
were able to determine that the rupture propagated 1,000 miles from south
to north at 5,000 miles per hour during the first 10 minutes of the
earthquake.
University of Colorado at Boulder - http://www.colorado.edu |
| Plasma
Escapes Newborn Star |

Using highly-resolved images from the Hubble Space
Telescope, a international team of astronomers at Rice
University and four other institutions created the first
moving pictures of a stellar jet. These massive streams
of plasma spew from the poles of newborn stars, playing
a critical, yet poorly understood role in star formation.
(Patrick Hartigan/ Rice University) |
Rice University
News Release
December 5, 2005 - Like traffic on a freeway, plasma spewing from the
poles of newborn stars moves in clumps that travel at different speeds.
When fast-moving particles run into slower material on these cosmic
freeways, the resulting "traffic jams" create massive shock
waves that travel trillions of miles.
Thanks to highly resolved images from the Hubble Space Telescope, a team
of astronomers have created the first moving pictures of one of these
cosmic freeways, which are known as stellar jets. The movies allow
scientists to trace these stellar jet shock waves for the first time,
gleaning important clues about a critical, yet poorly understood process
of starbirth. The results appeared in the November issue of Astronomical
Journal.
"When it comes to actually showing exactly what's going on, there's
just nothing like a movie," said study co-author Patrick Hartigan,
associate professor of physics and astronomy at Rice University. "You
can look at a still image and make up all kinds of stories, but they all
go out the window when you see a movie."
Hartigan and researchers from the Cerro Tololo Inter-American Observatory
(CTIAO) in Chile, Arizona State University (ASU), the University of Hawaii
and the University of Colorado at Boulder, made the movies using images
taken in 1994 and 1999 of a newly formed star called HH 47 in the
constellation Vela.
Because Hubble flies above the Earth's atmosphere, it can take much
clearer images than Earth-based telescopes. As a result, Hartigan and his
co-researchers were able to resolve objects in the Hubble images that were
20 times smaller than objects resolved in similar images taken on Earth.
This extra resolution, and the five-year gap between Hubble surveys of HH
47, allowed them to make moving pictures of the stellar jet shock waves
moving away from the new star.

(Patrick
Hartigan/ Rice University) |
"Imagine
taking a photo at a football game that shows the quarterback throwing the
ball at the start of a play," Hartigan said. "There is no way to
know what happened in the play without a second photograph at the end of
the play that shows a touchdown, incomplete pass, interception, or
whatever occurs. If you take a series of photos, with enough resolution to
make out the ball, you could determine whether someone ran with the ball
or caught a pass, and you could determine the relative position of all of
the players to one another at any time during the play.
"Like the time-lapse images of the game, our movies give us the
ability to track the movement of individual features within the stellar
jet, both relative to stationary objects and relative to other objects
that are moving within the jet at a different speed," Hartigan said.
New stars form out of giant clouds of gas and dust. Within these clouds,
strong gravitational forces pull material together into a tight ball
surrounded by a large spinning disk. The new star forms out of the ball,
and any planets that might form do so in the disk.
Through processes not well-understood, much of the disk material gradually
spirals into the star, and the resulting energy from this process drives
stellar jets of plasma that erupt from the star at perpendicular angles to
the spinning accretion disk. The material thrown away from the star in the
jets acts as a brake on disk, slowing its rotation and allowing more
material to fall into the growing star. Scientists know stellar jets play
an integral role in star formation, but they have yet to determine the
specifics of their role, or how it is carried out.
The research was funded by NASA. Co-authors on the study include CTIO's
Steve Heathcote, ASU's Jon A. Morse, University of Hawaii's Bo Reipurth
and University of Colorado at Boulder's John Bally.
Rice University - http://www.rice.edu |
| Mapping
Dark Matter |

On the left hand side is an ACS image that shows the lensed
galaxy elongated vertically by gravity. However, when the
same galaxy is observed with the Very Large Telescope (VLT)
at Cerro Paranal, we only see a small blob indicating no hints
of lensing (right panel). The shape information has been
destroyed by the atmospheric turbulence even if it is much
weaker there than at the sea level. (JHU) |
Johns Hopkins
University News Release
December 9, 2005 - Clues revealed by the recently sharpened view of the
Hubble Space Telescope have allowed astronomers to map the location of
invisible "dark matter" in unprecedented detail in two very
young galaxy clusters.
A Johns Hopkins University-Space Telescope Science Institute team reports
its findings in the December issue of Astrophysical Journal.
Other,
less-detailed observations appeared in the January 2005 issue of that
publication.
The team's results lend credence to the theory that the galaxies we can
see form at the densest regions of "cosmic webs" of invisible
dark matter, just as froth gathers on top of ocean waves, said study
co-author Myungkook James Jee, assistant research scientist in the Henry
A. Rowland Department of Physics and Astronomy in Johns Hopkins' Krieger
School of Arts and Sciences.
"Advances in computer technology now allow us to simulate the entire
universe and to follow the coalescence of matter into stars, galaxies,
clusters of galaxies and enormously long filaments of matter from the
first hundred thousand years to the present," Jee said.
"However, it is very challenging to verify the simulation results
observationally, because dark matter does not emit light."
Jee said the team measured the subtle gravitational "lensing"
apparent in Hubble images -- that is, the small distortions of galaxies'
shapes caused by gravity from unseen dark matter -- to produce its
detailed dark matter maps. They conducted their observations in two
clusters of galaxies that were forming when the universe was about half
its present age.
"The images we took show clearly that the cluster galaxies are
located at the densest regions of the dark matter haloes, which are
rendered in purple in our images," Jee said.

This is the snapshot of the computer simulation
of the dark matter Universe. These filamentary
structures are called "cosmic webs" of dark matter. |
The work buttresses
the theory that dark matter - which constitutes 90 percent of matter in
the universe -- and visible matter should coalesce at the same places
because gravity pulls them together, Jee said. Concentrations of dark
matter should attract visible matter, and as a result, assist in the
formation of luminous stars, galaxies and galaxy clusters.
Dark matter presents one of the most puzzling problems in modern
cosmology. Invisible, yet undoubtedly there -- scientists can measure its
effects -- its exact characteristics remain elusive. Previous attempts to
map dark matter in detail with ground-based telescopes were handicapped by
turbulence in the Earth's atmosphere, which blurred the resulting images.
"Observing through the atmosphere is like trying to see the details
of a picture at the bottom of a swimming pool full of waves," said
Holland Ford, one of the paper's co-authors and a professor of physics and
astronomy at Johns Hopkins.
The Johns Hopkins-STScI team was able to overcome the atmospheric obstacle
through the use of the space-based Hubble telescope. The installation of
the Advanced Camera for Surveys in the Hubble three years ago was an
additional boon, increasing the discovery efficiency of the previous HST
by a factor of 10.
The team concentrated on two galaxy clusters (each containing more than
400 galaxies) in the southern sky.
"These images
were actually intended mainly to study the galaxies in the clusters, and
not the lensing of the background galaxies," said co-author Richard
White, a STScI astronomer who also is head of the Hubble data archive for
STScI. "But the sharpness and sensitivity of the images made them
ideal for this project. That's the real beauty of Hubble images: They will
be used for years for new scientific investigations."
The result of the
team's analysis is a series of vividly detailed, computer-simulated images
illustrating the dark matter's location. According to Jee, these images
provide researchers with an unprecedented opportunity to infer dark
matter's properties.

Computer
simulation of the universe (NASA) |
The clumped
structure of dark matter around the cluster galaxies is consistent with
the current belief that dark matter particles are
"collision-less," Jee said. Unlike normal matter particles,
physicists believe, they do not collide and scatter like billiard balls
but rather simply pass through each other.
"Collision-less particles do not bombard one another, the way two
hydrogen atoms do. If dark matter particles were collisional, we would
observe a much smoother distribution of dark matter, without any
small-scale clumpy structures," Jee said.
Ford said this study demonstrates that the ACS is uniquely advantageous
for gravitational lensing studies and will, over time, substantially
enhance understanding of the formation and evolution of the cosmic
structure, as well as of dark matter.
"I am enormously gratified that the seven years of hard work by so
many talented scientists and engineers to make the Advanced Camera for
Surveys is providing all of humanity with deeper images and understandings
of the origins of our marvelous universe," said Ford, who is
principal investigator for ACS and a leader of the science team.
The ACS science and engineering team is concentrated at the Johns Hopkins
University and the Space Telescope Science Institute on the university's
Homewood campus in Baltimore. It also includes scientists from other major
universities in the United States and Europe. ACS was developed by the
team under NASA contract NAS5-32865 and this research was supported by
NASA grant NAG5-7697.
For graphics that illustrate this research, click on the following link: http://www.jhu.edu/news/home05/dec05/darkpix.html |