|
Orion
Spacecraft!
BrainTrek, BDTs,
Space Ether!
Hostile Holes, Safe Nanoparticles,
Gas on Mars! Chimps With Hammers! |
| Orion
Spacecraft! |

NASA's Constellation Program is getting to work on the new
spacecraft that will return humans to the moon and blaze a
trail to Mars and beyond. This artist's rendering represents a
concept of a crew exploration vehicle (CEV) and service
module. (NASA) |
NASA News Release
August 22, 2006 - NASA announced Tuesday that its new crew exploration
vehicle will be named Orion. Orion is the vehicle NASA’s Constellation
Program is developing to carry a new generation of explorers back to the
moon and later to Mars. Orion will succeed the space shuttle as NASA's
primary vehicle for human space exploration.
Orion's first flight with astronauts onboard is planned for no later than
2014 to the International Space Station. Its first flight to the moon is
planned for no later than 2020.
Orion is named for one of the brightest, most familiar and easily
identifiable constellations.
"Many of its stars have been used for navigation and guided explorers
to new worlds for centuries," said Orion Project Manager Skip
Hatfield. "Our team, and all of NASA - and, I believe, our country -
grows more excited with every step forward this program takes. The future
for space exploration is coming quickly."

After driving a short distance from their landing site, two
explorers stop to inspect a robotic lander and its small rover
in this artist's concept of a future Mars mission. (NASA/ Pat
Rawlings, SAIC) |
In June, NASA
announced the launch vehicles under development by the Constellation
Program have been named Ares, a synonym for Mars. The booster that will
launch Orion will be called Ares I, and a larger heavy-lift launch vehicle
will be known as Ares V.
Orion will be capable of transporting cargo and up to six crew members to
and from the International Space Station. It can carry four crewmembers
for lunar missions. Later, it can support crew transfers for Mars
missions.
Orion borrows its shape from space capsules of the past, but takes
advantage of the latest technology in computers, electronics, life
support, propulsion and heat protection systems. The capsule's conical
shape is the safest and most reliable for re-entering the Earth’s
atmosphere, especially at the velocities required for a direct return from
the moon.
Orion will be 16.5 feet in diameter and have a mass of about 25 tons.
Inside, it will have more than 2.5 times the volume of an Apollo capsule.
The spacecraft will return humans to the moon to stay for long periods as
a testing ground for the longer journey to Mars.
NASA's Johnson Space Center, Houston, manages the Constellation Program
and the agency's Marshall Space Flight Center, Huntsville, Ala., manages
the Exploration Launch Projects' office for the Exploration Systems
Mission Directorate, Washington.
NASA - http://www.nasa.gov |
| BrainTrek |

Depressed mouse |
McGill University News
Release
Montreal August 22, 2006 - A new breed of permanently 'cheerful' mouse is
providing hope of a new treatment for clinical depression. TREK-1 is a
gene that can affect transmission of serotonin in the brain. Serotonin is
known to play an important role in mood, sleep and sexuality. By breeding
mice with an absence of TREK-1, researchers were able create a
depression-resistant strain.
The details of this research, which involved an international
collaboration with scientists from the University of Nice, France, are
published in Nature Neuroscience this week.
"Depression is a devastating illness, which affects around 10% of
people at some point in their life," says Dr. Guy Debonnel an MUHC
psychiatrist, professor in the Department of Psychiatry at McGill
University, and principal author of the new research. "Current
medications for clinical depression are ineffective for a third of
patients, which is why the development of alternate treatments is so
important."
Mice without the TREK-1 gene ('knock-out' mice) were created and bred in
collaboration with Dr. Michel Lazdunski, co-author of the research, in his
laboratory at the University of Nice, France.

Happy mouse (Paul Terry) |
"These
'knock-out' mice were then tested using separate behavioral,
electrophysiological and biochemical measures known to gauge 'depression'
in animals," says Dr. Debonnel. "The results really surprised
us; our 'knock-out' mice acted as if they had been treated with
antidepressants for at least three weeks."
This research represents the first time depression has been eliminated
through genetic alteration of an organism. "The discovery of a link
between TREK-1 and depression could ultimately lead to the development of
a new generation of antidepressant drugs," noted Dr. Debonnel.
According to Health Canada and Statistics Canada, approximately 8% of
Canadians will suffer from depression at some point in their lifetime.
Around 5% of Canadians seek medical advice for depression each year; a
figure that has almost doubled in the past decade. Figures in the U.S. are
comparable, with approximately 18.8 million American adults (about 9.5% of
the population) suffering depression during their life.
McGill University - http://www.mcgill.ca |
| Bush
Wrong On Nuke Power? |
Massachusetts
Institute of Technology News Releas
By Anne Trafton
CAMBRIDGE August 22, 2006 - The Bush administration is eagerly pushing
nuclear power as a way to help solve the U.S. energy crisis. But in its
new plan for nuclear waste management, the administration is taking the
wrong approach, says an MIT professor who studies the nuclear energy
industry.
"My hope is that over time, the administration will rethink its
priorities in this area," says Richard Lester, professor of nuclear
engineering and director of the Industrial Performance Center.
In a recent article published in Issues in Science and Technology, Lester
argued that the Bush administration's plan, known as GNEP (Global Nuclear
Energy Partnership), is not the best way to encourage further development
of nuclear energy.

Oops, there goes another nuclear
containment facility... (LLNL) |
GNEP, which
President Bush announced earlier this year, is meant to stimulate the
nuclear industry by coming up with better ways to manage spent nuclear
fuel. The plan focuses on reprocessing spent fuel, but Lester believes the
administration should focus on finding regional storage facilities for the
nuclear waste.
Right now, uncertainty over how to deal with spent fuel, which remains
radioactive for hundreds of thousands of years, is one of the major
obstacles to the construction of new plants. Thousands of spent fuel rods
are now stored in secure pools or concrete casks located near nuclear
plants, which is not considered a long-term solution.
The administration has been pushing a plan to move all of the nation's
spent fuel to a repository at Yucca Mountain, Nevada, but that facility is
not scheduled to open until at least 2017. Many years and billions of
dollars have gone into planning for the repository there, over the
protests of Nevada residents, and success is still not assured. If
the project fails, an alternative will be needed. And even if it succeeds,
spent fuel will remain at nuclear power plants for decades before it can
be removed.
Several nuclear energy companies have sued the federal government for
failing to fulfill its contractual obligation to remove spent nuclear fuel
from their plants. That failure does not bode well for construction of new
plants, Lester said.
"If electric power companies can't believe the government is going to
fulfill its obligations, it's going to be a real deterrent for them to go
ahead with new power plants," he said.
In the meantime, the Bush plan calls for developing new technology to
reprocess spent fuel to recover usable plutonium and uranium and eliminate
other long-lived radioactive elements known as actinides. But according to
Lester, the government's efforts would be better focused on other
solutions, such as establishing a small number of regional facilities,
where nuclear plants could send their spent fuel to be stored safely for
several decades.
GNEP does not address the utilities' spent fuel storage problem. Instead,
it "is being sold as a technical fix for three other problems,"
Lester said, but "each of these problems is either not as serious as
the administration suggests or could be solved in a different way that is
less costly and less risky."
Those perceived problems are lack of space at Yucca Mountain; the long
life of radioactive material; and a potential shortage of uranium.
 |
Yucca Mountain, a
ridgeline geological formation about 100 miles northwest of Las Vegas, has
already been tunneled in preparation for waste storage. When Congress
approved the Yucca Mountain site, it put a 70,000-metric-ton limit on the
amount of waste that could be stored there, but there is room for much
more if Congress wants to raise the limit, Lester said.
Any effort to remove the long-lived radioactivity from the waste would
require construction of reprocessing plants, special "burner"
reactors and other nuclear facilities, which would be costly and difficult
to site. And even if these plants were successfully built, it would be
nearly impossible to eliminate all of the long-lived radioisotopes in the
waste, Lester says.
"When you really look at the technical feasibility of reducing the
toxic lifetime of waste, it has less potential than the administration is
claiming, and the costs and shorter-term risks of doing it are
significant," he said. Moreover, according to Lester, there are
other, less costly ways to reduce the long-term risks of nuclear waste
disposal that the administration has ignored.
Supporters of GNEP also say that reprocessing spent fuel could be
necessary in the future if uranium becomes scarce, but according to the
2003 MIT report, "The Future of Nuclear Power," there is enough
uranium to last for several decades, even if many new nuclear plants are
built.
Lester said he is not opposed to research on new fuel cycle technologies,
but he argues that reprocessing will not be needed for several decades, if
then, and that to spend billions of dollars over the next few years on
demonstrating reprocessing and related technologies, as the administration
is proposing, would not be a wise use of resources.
Massachusetts Institute of Technology - http://web.mit.edu/newsoffice |
| BDTs
- Ballistic Deflection Transistors |

Ballistic Transistor at work. (UR) |
University of
Rochester News Release
August 16, 2006 - Computer designers at the University of Rochester are
going ballistic.
"Everyone has been trying to make better transistors by modifying
current designs, but what we really need is the next paradigm," says
Quentin Diduck, a graduate student at the University who thought up the
radical new design. "We've gone from the relay, to the tube, to
semiconductor physics. Now we're taking the next step on the evolutionary
track."
That next step goes
by the imposing name of "Ballistic Deflection Transistor," and
it's as far from traditional transistors as tubes. Instead of running
electrons through a transistor as if they were a current of water, the
ballistic design bounces individual electrons off deflectors as if playing
a game of atomic billiards.
Though today's transistor design has many years of viability left, the
amount of heat these transistors generate and the electrical
"leaks" in their ultra-thin barriers have already begun to limit
their speed.
Research groups
around the world are investigating strange new designs to generate ways of
computing at speeds unthinkable with today's chips. Some of these groups
are working on similar single-electron transistors, but these designs
still compute by starting and stopping the flow of electrons just like
conventional designs. But the Ballistic Deflection Transistor adds a new
twist by bouncing the electrons into their chosen trajectories—using
inertia to redirect for "free," instead of wrestling the
electrons into place with brute energy.
Such a chip would use very little power, create very little heat, be
highly resistant to "noise" inherent in electronic systems, and
should be easy to manufacture with current technologies. All that would
make it incredibly fast. The National Science Foundation is so impressed
with the idea that it just granted the University of Rochester team $1.1
million to develop a prototype.
"We've assembled a unique team to take on this chip," says Marc
Feldman, professor of computer engineering at the University. "In
addition to myself and Quentin, we have a theoretical physicist, a circuit
designer, and an expert in computer architecture. We're not just designing
a new transistor, but a new archetype as well, and as far as I know, this
is the first time an architect has been involved in the actual design of
the transistor on which the entire architecture is built."
The team has already had some luck in fabricating a prototype. The
ballistic transistor is a nano-scale structure, and so all but impossible
to engineer just a few years ago. Its very design means that this
"large" prototype is already nearly as small as the best
conventional transistor designs coming out of Silicon Valley today.
Feldman and Diduck are confident that the design will readily scale to
much smaller dimensions.
There's one hurdle the team isn't quite as confident about: "We're
talking about a chip speed measured in terahertz, a thousand times faster
than today's desktop transistors" Diduck says. "We have to
figure out how to test it because there's no such thing as a terahertz
oscilloscope!"
The Science Behind the Ballistics
The Ballistic Deflection Transistor (BDT) should produce far less heat and
run far faster than standard transistors because it does not start and
stop the flow of its electrons the way conventional designs do. It
resembles a roadway intersection, except in the middle of the intersection
sits a triangular block. From the "south" an electron is fired,
as it approaches the crossroads, it passes through an electrical field
that pushes the electron slightly east or west. When the electron reaches
the middle of the intersection, it bounces off one side of the triangle
block and is deflected straight along either the east or west roads. In
this way, if the electron current travels along the east road, it may be
counted as a zero, and as a one if it travels down the west road.
A traditional transistor registers a "one" as a collection of
electrons on a capacitor, and a "zero" when those electrons are
removed. Moving electrons on and off the capacitor is akin to filling and
emptying a bucket of water. The drawback to this method is that it takes
time to fill and empty that bucket. That refill time limits the speed of
the transistor—the transistors in today's laptops run at perhaps two
gigahertz, meaning two billion refills every second. A second drawback is
that these transistors produce immense amounts of heat when that energy is
emptied.
The BDT design should also be able to resist much of the electrical noise
present in all electronic devices because the noise would only be present
in the electrical "steering" field, and calculations show the
variations of the noise would cancel themselves out as the electron passes
through.
The BDT is "ballistic" because it is made from a sheet of
semiconductor material called a "2D electron gas," which allows
the electrons to travel without hitting impurities, which would impede the
transistor's performance.
The BDT prototype was fabricated at the Cornell Nanofabrication Facility
with the support provided by the Office of Naval Research.
The $1.1 million is an NSF Nanotechnology Integrated Research Team grant,
which is only awarded to promising research. The team is comprised of Marc
Feldman, professor of electrical and computer engineering, Martin Margala
and Paul Ampadu, assistant professors of electrical and computer
engineering, and Yonathan Shapir, professor of physics and astronomy.
To see an animation, go to http://www.rochester.edu/news/photos/hi_res/BallisticTransistor/BallisticMovie.wmv
University of Rochester - http://www.rochester.edu |
| Dark
Matter Exists! |
University
of Arizona News Release
By Lori Stiles
August 21, 2006 - Astronomers have discovered first direct proof that dark
matter exists. University of Arizona astronomers and their colleagues got
side-on views of two merging galaxy clusters in observations made with
state-of-the-art optical and X-ray telescopes.
"Nature gave
us this fantastic opportunity to see hypothesized dark matter separated
from ordinary matter in this merging system," said UA astronomer
Douglas Clowe, leader of the study.
"Prior to this observation, all of our cosmological models were based
on an assumption that we couldn't prove: that gravity behaves the same way
on the cosmic scale as on Earth," Clowe said. "The clusters
we've looked at in these images are a billion times larger than the
largest scales at which we can measure gravity at present, which are on
the scale of our solar system."
Clowe added, "What's amazing about this is that the process of galaxy
clusters merging is thought to go on all of time. That's how galaxy
clusters gain mass. But the fact that we caught this thing only 100
million years after it occurred -- so recently that it barely registers on
the cosmic time scale -- is tremendous luck."

This composite image shows the galaxy cluster 1E0657-556, also
known as the "bullet cluster", formed after the collision
of two large
clusters of galaxies. Hot gas detected by Chandra is seen as two
pink
clumps in the image and contains most of the "normal"
matter in the
two clusters. An optical image from Magellan and the Hubble Space
Telescope shows galaxies in orange and white. The blue clumps show
where most of the mass in the clusters is found, using a technique
known as gravitational lensing. Most of the matter in the clusters
(blue) is clearly separate from the normal matter (pink), giving
direct evidence that nearly all of the matter in the clusters is
dark.
This result cannot be explained by modifying the laws of gravity.
(NASA/ CXC /M.Markevitch /STScI; Magellan /U.Arizona/ D.Clowe et al.
ESO WFI) |
Astronomers have
known since the 1930s that most of the universe must be made up of
something other than normal matter, the stuff that makes stars, planets,
all things and creatures. Given the way that galaxies move through space
and scientists' understanding of gravity, astronomers theorize that the
universe must contain about five times more dark matter than normal
matter.
But for the past 70 years, no one had any direct empirical evidence that
dark matter even exists.
"Astronomers have been in the somewhat embarrassing position of
saying that we understand the universe, although more than 80 percent of
it is something we don't know anything about," said UA astronomy
Professor Dennis Zaritsky, a member of the discovery team.
"Either most of the matter in the universe is in some invisible,
undiscovered form we call 'dark matter' that causes galaxies to move as
they do, or we just don't understand the fundamental laws of
gravity," Zaritsky said.
When galaxy clusters merge, the galaxies themselves are so sparsely
scattered in space that they don't collide, Clowe said. "Even if two
galaxies do pass through each other, the distance between the stars is so
great that even stars won't collide. Galaxies basically plow through each
other almost without slowing down."
Most of a galaxy cluster's normal mass is in its diffuse hot gas. Galaxy
clusters typically contain 10 times as much ordinary mass in gas as in
stars. So when galaxy clusters merge, the hot gas from each cluster exerts
a drag force on the other, slowing all the gas down, Clowe said.The upshot
is that the galaxies themselves continue speeding through space, leaving
the gas behind.
Observations made with NASA's Chandra X-ray Observatory showed the bulk of
ordinary matter is in the hot gas clouds left in the wake of the galaxies.
Part of this million-degree plasma of hydrogen and helium, the part from
the smaller cluster, forms a spectacular bullet-shaped cloud because a bow
shock, or supersonic shock wave, is created in the 10 million mph
collision.
But when the astronomers mapped the region of the sky around the galaxies
in optical light, they discovered far more mass near the galaxies, ahead
of the gas cloud. They analyzed gravitational lensing of distant galaxies
in images taken with NASA's Hubble Space Telescope, the European Southern
Observatory's 2-meter Wide-Field Imager and one of the twin 6.5-meter
Magellan telescopes that a consortium that includes UA operates in Chile.
Gravitational lensing is a phenomenon caused by gravity bending distant
starlight. When the astronomers analyzed the shapes and patterns of the
distorted light, they discovered the mass of non-luminous, or dark, matter
that causes the lensing is far greater than the mass of ordinary matter in
the gas cloud.
Clowe and Zaritsky said that dark matter particles are not expected to
interact with either normal matter or dark matter particles except through
gravity. Hence, they would pass through the collision just as galaxies do.
"We see that dark matter has careened through the collision
efficiently," Zaritsky said.
"We're actually using this system to test the idea that dark matter
particles are collisionless," Clowe said.
"The bottom line is, there really is dark matter out there,"
Zaritsky said. "Now we just need to figure out what it is."
The team is publishing the research in a forthcoming issue of the
Astrophysical Journal Letters. In addition to Clowe and Zaritsky of UA's
Steward Observatory, team members include Marusa Bradac of the Kavli
Institute for Particle Astrophysics and Cosmology in Stanford, Calif.,
Anthony Gonzalez of the University of Florida, and Maxim Markevitch, Scott
Randall and Christine Jones of the Harvard-Smithsonian Center for
Astrophysics.
University of Arizona - http://uanews.org |
| Space
Ether - Dark Matter Doesn't Exist! |

They posit an ether that is a field, rather than a substance, and
which pervades
space-time. |
New Scientist News
Release
August 23, 2006 - From his office window, Glenn Starkman can see the site
where Albert Michelson and Edward Morley carried out their famous 1887
experiment that ruled out the presence of an all-pervading
"aether" in space, setting the stage for Einstein's special
theory of relativity.
So it seems ironic that Starkman, who is at Case Western Reserve
University in Cleveland, Ohio, is now proposing a theory that would bring
ether back into the reckoning. While this would defy Einstein, Starkman's
ether would do away with the need for dark matter.
Nineteenth-century physicists believed that just as sound waves move
through air, light waves must move through an all-pervading physical
substance, which they called luminiferous ("light-bearing")
ether. However, the Michelson-Morley experiment failed to find any signs
of ether, and 18 years after that, Einstein's special relativity argued
that light propagates through a vacuum. The idea of ether was abandoned
– but not discarded altogether, it seems.
Starkman and colleagues Tom Zlosnik and Pedro Ferreira of the University
of Oxford are now reincarnating the ether in a new form to solve the
puzzle of dark matter, the mysterious substance that was proposed to
explain why galaxies seem to contain much more mass than can be accounted
for by visible matter. They posit an ether that is a field, rather than a
substance, and which pervades space-time. "If you removed everything
else in the universe, the ether would still be there," says Zlosnik.
This ether field
isn't to do with light, but rather is something that boosts the
gravitational pull of stars and galaxies, making them seem heavier, says
Starkman. It does this by increasing the flexibility of space-time itself.
"We usually imagine space-time as a rubber sheet that's warped by a
massive object," says Starkman. "The ether makes that rubber
sheet more bendable in parts, so matter can seem to have a much bigger
gravitational effect than you would expect from its weight." The
team's calculations show that this ether-induced gravity boost would
explain the observed high velocities of stars in galaxies, currently
attributed to the presence of dark matter.
This is not the first time that physicists have suggested modifying
gravity to do away with this unseen dark matter. The idea was originally
proposed by Mordehai Milgrom while at Princeton University in the 1980s.
He suggested that the inverse-square law of gravity only applies where the
acceleration caused by the field is above a certain threshold, say a0.
Below that value, the field dissipates more slowly, explaining the
observed extra gravity. "It wasn't really a theory, it was a
guess," says cosmologist Sean Carroll at the University of Chicago in
Illinois.

Starkman's team must now carefully check whether
the ether theory fits with the motions of planets
within our solar system. (NASA) |
Then in 2004 this
idea of modified Newtonian dynamics (MOND) was reconciled with general
relativity by Jacob Bekenstein at the Hebrew University in Jerusalem,
Israel (New Scientist, 22 January 2005, p 10), making MOND a genuine
contender in the eyes of some physicists. Bekenstein's work was brilliant,
but fiendishly complicated, using many different and arbitrary fields and
parameters," says Ferreira. "We felt that something so
complicated couldn't be the final theory.
Now Starkman's team has reproduced Bekenstein's results using just one
field - the new ether. Even more tantalisingly, the calculations reveal a
close relationship between the threshold acceleration a0 - which depends
on the ether - and the rate at which the universe's expansion is
accelerating. Astronomers have attributed this acceleration to something
called dark energy, so in a sense the ether is related to this entity.
That they have found this connection is a truly profound thing, says
Bekenstein. The team is now investigating how the ether might cause the
universe's expansion to speed up.
Andreas Albrecht, a cosmologist at the University of Calfornia, Davis,
believes that this ether model is worth investigating further. "We've
hit some really profound problems with cosmology Ð with dark matter and
dark energy," he says. "That tells us we have to rethink
fundamental physics and try something new."
Both Bekenstein and Albrecht say Starkman's team must now carefully check
whether the ether theory fits with the motions of planets within our solar
system, which are known to a high degree of accuracy, and also explain
what exactly this ether is. Ferreira agrees: "The onus is definitely
on us to pin this theory down so it doesn't look like yet another
fantastical explanation," he says.
However, physicists may be reluctant to resurrect any kind of ether
because it contradicts special relativity by forming an absolute frame of
reference . "Interestingly, this controversial aspect should make it
easy to test for experimentally," says Carroll.
New Scientist - http://www.newscientist.com |
| Hostile
Black Holes! |

This artist's concept depicts a supermassive black hole at the
center of a galaxy.
The blue color here represents radiation pouring out from material
very close
to the black hole. The grayish structure surrounding the black hole,
called a
torus, is made up of gas and dust. (NASA/ JPL-Caltech) |
NASA News Release
August 23, 2006 - Supermassive black holes in some giant galaxies create
such a hostile environment, they shut down the formation of new stars,
according to NASA Galaxy Evolution Explorer findings published in the
August 24 issue of Nature.
The orbiting observatory surveyed more than 800 nearby elliptical galaxies
of various sizes. An intriguing pattern emerged: the more massive, or
bigger, the galaxy, the less likely it was to have young stars. Because
bigger galaxies are known to have bigger black holes, astronomers believe
the black holes are responsible for the lack of youthful stars.
"Supermassive black holes in these giant galaxies create unfriendly
places for stars to form," said Dr. Sukyoung K. Yi of Yonsei
University in Seoul, Korea, who led the research team. "If you want
to find lots of young stars, look to the smaller galaxies."
Previously, scientists had predicted that black holes might have dire
consequences for star birth, but they didn't have the tools necessary to
test the theory. The
Galaxy Evolution Explorer, launched in 2003, is well-suited for this
research.
It is extremely
sensitive to the ultraviolet radiation emitted by even low numbers of
young stars.
Black holes are monstrous heaps of dense matter at the centers of
galaxies. Over time, a black hole and its host galaxy will grow in size,
but not always at the same rate.
Yi and his collaborators found evidence that the black holes in elliptical
galaxies bulk up to a critical mass before putting a stop to star
formation. In other words, once a black hole reaches a certain size
relative to its host galaxy, its harsh effects become too great for new
stars to form. According to this "feedback" theory, the growth
of a black hole slows the development of not only stars but of its entire
galaxy.
How does a black hole do this? There are two possibilities. First, jets
being blasted out of black holes could blow potential star-making fuel, or
gas, out of the galaxy center, where stars tend to arise.
The second theory relates to the fact that black holes drag surrounding
gas onto them, which heats the gas. The gas becomes so hot that it can no
longer clump together and collapse into stars.
Other authors of this research include: Drs. Kevin Schawinski, Sadegh
Khochfar and Sugata Kaviraj of the University of Oxford, England; Dr.
Young-Wook Lee of Yonsei University in Seoul, Korea; Drs. Alessandro
Boselli, Jose Donas and Bruno Milliard of the Laboratory of Astrophysics
of Marseille, France; Tim Conrow, Drs. Tom Barlow, Karl Forster, Peter G.
Friedman, D. Chris Martin, Patrick Morrissey, Mark Seibert, Todd Small and
Ted K. Wyder of the California Institute of Technology in Pasadena; Dr.
Susan Neff of NASA's Goddard Space Flight Center, Greenbelt, Maryland; Dr.
David Schiminovich of Columbia University, N.Y.; Drs. Tim Heckman, Alex
Szalay and Luciana Bianchi of Johns Hopkins University, Baltimore, Md.;
Dr, Barry Madore of the Observatories of the Carnegie Institute of
Washington in Pasadena; and Dr. R. Michael Rich of the University of
California, Los Angeles.
Additional information about Galaxy Evolution Explorer is online at http://www.galex.caltech.edu
JPL / NASA - http://www.jpl.nasa.gov |
| Safe
Nanoparticles? |

Nanoparticles (NIST) |
Brookhaven National
Laboratory News Release
UPTON NY August 21, 2006 - Scientists at the U.S. Department of Energy’s
Brookhaven National Laboratory have developed a screening method to
examine how newly made nanoparticles — particles with dimensions on the
order of billionths of a meter — interact with human cells following
exposure for various times and doses.
This has led to the visualization of how human cells interact with some
specific types of carbon nanoparticles. The method is described in a
review article on carbon nanoparticle toxicity in a special section of the
August 23, 2006, issue of the Journal of Physics: Condensed Matter devoted
to developments in nanoscience and nanotechnology, now available online.
Nanoparticles may have different physical, chemical, electrical, and
optical properties than occur in bulk samples of the same material, in
part due to the increased surface area to volume ratio at the nanoscale.
Many scientists believe that understanding these nanoscale properties and
finding ways to engineer new nanomaterials will have revolutionary impacts
— from more efficient energy generation and data storage to improved
methods for diagnosing and treating disease.
Brookhaven Lab is currently building a Center for Functional Nanomaterials
(CFN) with state-of-the-art facilities for the fabrication and study of
nanomaterials, with an emphasis on atomic-level tailoring of nanomaterials
and nanoparticles to achieve desired properties and functions.
“Nanomaterials show great promise, but because of their extremely small
size and unique properties, little is known about their effects on living
systems,” said lead author Barbara Panessa-Warren, a Brookhaven
biologist who has been developing a nanoparticle cytotoxicity-screening
model for the past five years.
“Our experiments may provide scientists with information to help
redesign nanoparticles to minimize safety concerns, and to optimize their
use in health-related applications. They may also lead to effective
screening practices for carbon-based materials.”
A variety of studies conducted in living animals, which are described in
the review article, have found a range of toxic effects resulting from
exposure to carbon-based nanoparticles. All of these in vivo studies
clearly show that multiple factors interact following nanoparticle
exposure to produce acute and chronic changes within individual cells and
the organism itself.
In vitro laboratory studies, such as the cell-culture method developed by
the Brookhaven team, are an attempt to simplify the research by
eliminating many of the variables found in animal studies, giving
researchers greater control over experimental conditions.
“By combining techniques of molecular biology with sophisticated imaging
methods, we can rapidly gather information about the response of specific
cell types to specific nanoparticles, making in vitro testing an
inexpensive and immediate tool for screening and fine-tuning nanoparticle
design to maximize safety and target specificity,” Panessa-Warren said.
In the Brookhaven team’s studies, the scientists used lung and colon
epithelial cells — chosen to represent two likely routes of nanoparticle
exposure (inhalation and ingestion) — grown as cell monolayers, where
the individual cells join together to form a tight layer with many of the
characteristics of lung and colon cells growing in the body as an
epithelial layer. These monolayers of living cells are then exposed to
varying doses of carbon nanoparticles over differing amounts of time, and
the cells are studied at each time period and dose.
The scientists also tested the response of the cells to different types of
nanoparticles (a raw nanotube preparation containing mostly single-walled
carbon nanotubes, nanoropes, graphene and trace elements; partially
cleaned air-oxidized carbon nanotubes; as well as, carbon-nanotube-derived
loops used to carry antibodies).
They assessed cell viability (did the cells live or die?) and growth
characteristics of the monolayer, and examined any alterations within the
cells using various microscopy techniques. These techniques enabled them
to visualize the first contact of the nanoparticles with the cells and
follow this process “ultrastructurally” so they could see how the
cells responded and determine whether the nanoparticles entered the cells
or caused specific changes to the cell surfaces of those cells that did
not die.
Using this in vitro screening, the scientists found that a type of
engineered carbon nanoparticle called a ‘nanoloop,’ which was made at
Brookhaven, did not appear to be toxic to either cell type regardless of
dose and time. In contrast, both colon and lung cells exposed to carbon
nanoparticles from the raw nanotube preparation showed increased cell
death with increased exposure time and dose.
Microscopic studies revealed losses of cell-to-cell attachments in the
monolayers, and changes in cell-surface morphology on cells where carbon
nanotubes and other carbon nanoparticles had attached. Damage was severe
for both the low and higher doses at three hours, suggesting that exposure
time may be even more predictive of damage than nanoparticle
concentration.
Using electron microscopy, the scientists found that areas in which the
carbon nanoparticles, and especially carbon nanotubes, touched or attached
to the cell surface, the plasma membranes became damaged and were
microscopically interrupted. Images of the cell surfaces with attached
carbon nanoparticles showed membrane holes that exposed the underlying
cell cytoplasm.
Transmission
electron microscopy revealed that small carbon particles could pass into
the cells and become incorporated into the cell nuclei. Neighboring cells
with no attached carbon nanoparticles appeared normal and continued to
grow, suggesting that direct contact with untreated nanoparticles is
required for damage to occur.

Carbon nanoparticles
called fullerenes, also known
as “buckyballs.” |
These findings
agree with recent biochemical studies in the literature that reported the
production of reactive oxygen species (free radicals) and lipid
peroxidation of cell membranes following living cell contact with other
forms of carbon nanoparticles called fullerenes, also known as “buckyballs.”
“Although our screening method gives us a quick way to analyze human
cell responses to nanoparticles at a visual macro- and micro- scale, we
are now taking this to a molecular and genetic level to see whether the
cells are stressed,” said Pannessa-Warren.
“Ultimately any new nanomaterials intended for large-scale production or
use would also have to be tested in vivo — where the combined reactions
of many cell types and tissues, as well as the blood, immune, and hormonal
factors, are all taken into account to assess biocompatibility and assure
safety,” she added.
“Still, our methods give us a way to screen-out those nanoparticles that
shouldn’t even make it that far, or identify ways to improve them first.”
This research was funded by the Office of Basic Energy Sciences within the
U.S. Department of Energy’s Office of Science. The CFN at Brookhaven Lab
is one of five Nanoscale Science Research Centers being constructed at
national laboratories by the DOE’s Office of Science to provide the
nation with resources unmatched anywhere else in the world for synthesis,
processing, fabrication, and analysis at the nanoscale.
Brookhaven National Laboratory - http://www.bnl.gov |
| Gas
on Mars! |
NASA
News Release

Artist concept showing sand-laden jets shoot into the
Martian polar sky. (Arizona State University/ Ron Miller) |
August 16, 2006 -
Every spring brings violent eruptions to the south polar ice cap of Mars,
according to researchers interpreting new observations by NASA's Mars
Odyssey orbiter.
Jets of carbon dioxide gas erupting from the ice cap as it warms in the
spring carry dark sand and dust high aloft. The dark material falls back
to the surface, creating dark patches on the ice cap which have long
puzzled scientists. Deducing the eruptions of carbon dioxide gas from
under the warming ice cap solves the riddle of the spots. It also reveals
that this part of Mars is much more dynamically active than had been
expected for any part of the planet.
"If you were there, you'd be standing on a slab of carbon-dioxide
ice," said Phil Christensen of Arizona State University, Tempe,
principal investigator for Odyssey's camera. "All around you, roaring
jets of carbon dioxide gas are throwing sand and dust a couple hundred
feet into the air."
You'd also feel vibration through your spacesuit boots, he said. "The
ice slab you're standing on is levitated above the ground by the pressure
of gas at the base of the ice."
The team began its research in an attempt to explain mysterious dark
spots, fan-like markings, and spider-shaped features seen in images that
cameras on Odyssey and on NASA's Mars Global Surveyor have observed on the
ice cap at the Martian south pole.
The dark spots, typically 15 to 46 meters (50 to 150 feet) wide and spaced
several hundred feet apart, appear every southern spring as the sun rises
over the ice cap. They last for several months and then vanish -- only to
reappear the next year, after winter's cold has deposited a fresh layer of
ice on the cap. Most spots even seem to recur at the same locations.
An earlier theory proposed that the spots were patches of warm, bare
ground exposed as the ice disappeared. However, the camera on Odyssey,
which sees in both infrared and visible-light wavelengths, discovered that
the spots are nearly as cold as the carbon dioxide ice, suggesting they
were just a thin layer of dark material lying on top of the ice and kept
chilled by it. To understand how that layer is produced, Christensen's
team used the camera -- the Thermal Emission Imaging System -- to collect
more than 200 images of one area of the ice cap from the end of winter
through midsummer.

Dark spots (left) and 'fans' appear to scribble dusty hieroglyphics
on top
of the Martian south polar cap. (NASA/ JPL/ Malin Space Science
Systems) |
Some places
remained spot-free for more than 100 days, then developed many spots in a
week. Fan-shaped dark markings didn't form until days or weeks after the
spots appeared, yet some fans grew to half a mile in length. Even more
puzzling was the origin of the "spiders," grooves eroded into
the surface under the ice. The grooves converge at points directly beneath
a spot.
"The key to figuring out the spiders and the spots was thinking
through a physical model for what was happening," said Christensen.
The process begins in the sunless polar winter when carbon dioxide from
the atmosphere freezes into a layer about three feet thick on top of a
permanent ice cap of water ice, with a thin layer of dark sand and dust in
between. In spring, sunlight passing through the slab of carbon dioxide
ice reaches the dark material and warms it enough that the ice touching
the ground sublimates -- turns into gas.
Before long, the swelling reservoir of trapped gas lifts the slab and
eventually breaks through at weak spots that become vents.
High-pressure gas
roars through at speeds of 161 kilometers per hour (100 miles per hour) or
more. Under the slab, the gas erodes ground as it rushes toward the vents,
snatching up loose particles of sand and carving the spidery network of
grooves.
Christensen, Hugh Kieffer (U.S. Geological Survey, retired) and Timothy
Titus (USGS) report the new interpretation in the Aug. 17, 2006, issue of
the journal "Nature."
JPL, a division of the California Institute of Technology, Pasadena,
manages Mars Odyssey and Mars Global Surveyor missions for the NASA
Science Mission Directorate. Odyssey's Thermal Emission Imaging System is
operated by Arizona State University.
For additional information about Odyssey and the new findings, visit http://www.nasa.gov/mars
and http://themis.asu.edu |
| Chimps
With Hammers! |

It may indicate that nut-cracking has been invented [by chimps]
on more than one occasion in widely separated populations. |
Cell Press News
Release
August 21, 2006 - In a finding that challenges a long-held belief
regarding the cultural spread of tool use among chimpanzees, researchers
report that chimpanzees in the Ebo forest, Cameroon, use stone hammers to
crack open hard-shelled nuts to access the nutrient-rich seeds.
The findings are significant because this nut-cracking behavior was
previously known only in a distant chimpanzee population in extreme
western Africa and was thought to be restricted by geographical boundaries
that prevented cultural spread of the technique from animal to animal.
The findings, which involve the most endangered and least-understood
subspecies of chimpanzee, are reported by Dr. Bethan Morgan and Ekwoge
Abwe of the Zoological Society of San Diego's Conservation and Research
for Endangered Species (CRES) and appear in the August 22nd issue of the
journal Current Biology, published by Cell Press.
Prior to this discovery, it was thought that chimpanzee nut-cracking
behavior was confined to the region west of the N'Zo-Sassandra River in
Cote d'Ivoire. Because there are no relevant ecological or genetic
differences between populations on either side of this "information
barrier," explain the researchers of the new study, the implication
had been that nut-cracking is a behavioral tradition constrained in its
spread by a physical barrier:
It was absent to the east of the river because it had not been invented
there. The new finding that chimpanzees crack open nuts more than 1700 km
east of the supposed barrier challenges this long-accepted model.
According to the authors of the study, the discontinuous distribution of
the nut-cracking behavior may indicate that the original "culture
zone" was larger, and nut-cracking behavior has become extinct
between the N'Zo-Sassandra and Ebo.
Alternatively, it may indicate that nut-cracking has been invented on more
than one occasion in widely separated populations.
This is one of the first reports of tool use for Pan troglodytes
vellerosus, the most endangered and understudied chimpanzee subspecies. It
highlights the necessity to preserve the rich array of cultures found
across chimpanzee populations and communities, which represent our best
model for understanding the evolution of hominid cultural diversity.
As such, the new finding promises to both benefit research and inform the
conservation of our closest living relative.
Cell Press - http://www.cellpress.com |