On February 3, 1939, Orson Welles and the Campbell Playhouse present Arrowsmith
by Sinclair Lewis. Cast: Orson Welles (Martin Arrowsmith), Helen Hayes (Leora
Arrowsmith), Ray Collins (Professor Gottlieb), Frank Readick (Sondelius), Al
Swenson (Henry Novak), Effie Palmer (Mrs. Tozer), Everette Sloane (Mr. Tozer),
Carl Frank (Dr. Stoups).

American author Sinclair Lewis won the 1926 Pulitzer Prize (which he declined)
for Arrowsmith. Lewis was greatly assisted in its preparation by science writer
Paul de Kruif, who received 25% of the royalties on sales, although Lewis was
listed as the sole author. (wiki)

The 1931 film version was directed by John Ford, starring Ronald Colman, Helen
Hayes, Richard Bennett and Myrna Loy. Arrowsmith was nominated for four Oscars,
including the Academy Award for Best Picture, Best Writing / Adaptation (Sidney
Howard), Best Cinematography (Ray June), and Best Art Direction (Richard Day).